Which Teratogenic Effect Is Seen Due To Lithium in How To

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Which Teratogenic Effect Is Seen Due To Lithium. The results of various studies including cohort, prospective, retrospective and small number case reports indicate that lithium is a weak teratogen in humans. Teratogenicity depends upon the ability of the agent to cross the placenta.

PPT Psychiatric medications in pregnancy and lactation
PPT Psychiatric medications in pregnancy and lactation from www.slideserve.com

Lithium is a broadly used psychiatric drug that was found to be teratogenic in the mouse , but its effect on the human embryo is yet unresolved. Teratogenic effects of lithium chloride on eye development in early embryogenesis of zebrafish (danio rerio) christina m. Ibuprofen is a nsaid that may cause premature closure of the ductus arterioles as a teratogenic effect.

PPT Psychiatric medications in pregnancy and lactation

Thus, serum lithium levels should be monitored. 10 however, there is a small risk and lithium is best avoided during pregnancy. Certain medications such as heparin cannot cross the placenta due to its high molecular Lithium because ebstein anomaly as a teratogenic effect.